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Scientists Print Human Cells on 3D Printer

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Heriot-Watt-University’s-Biomedical-Microengineering-group-Roslin-Cellab-3D-bioprinting
(TVNZ) – For the first time, scientists have printed human embryonic stem cells using a 3D printer.

Using stem cells as a form of ink, the Heriot-Watt University team led by Dr Will Wenmiao Shu think they will soon be able to print human tissue.

Bioengineer Alan Faulkner-Jones built the printer using parts from an old 3D printer. It uses a valve-based technique to deposit whole life cells onto a surface.

The team printed tiny droplets of bio ink, each containing up to five cells
from an embryonic human kidney and an embryonic cell line.

Ninety-nine percent of cells tested were alive and viable for replication.

“It’s accurate enough to produce 3D micro-tissue.” said Dr Shu.

“The printed cells can still maintain their potency, which is their ability to differentiate into any other cell types in our body.”

That differentiation occurs when the stem cells are combined with nascent cells from specific organs, like the liver or lungs, which emit chemical signals to transform the stem cells into liver or lung tissue.

Dr Shu’s team want to produce human liver tissue by 2015 and build individual organs with their stem cell printer soon after.

(Inhabitat) – The process – developed by Dr. Will Shu and his colleagues at Heriot-Watt University’s Biomedical Microengineering group in partnership with Roslin Cellab – is different from previous 3D cell printing attempts because it can produce delicate embryonic cell cultures. Prior to this, printing could only produce 2D cells or cells that are tougher than human stem cells. “To the best of our knowledge, this is the first time that these cells have been 3D printed. The technique will allow us to create more accurate human tissue models which are essential to in vitro drug development and toxicity-testing,” says Dr. Shu.

The technology could provide doctors with an endless supply of organs for transplantation, and it could entirely eliminate the practice of animal drug testing. According to Dr. Shu, “In the longer term, we envisage the technology being further developed to create viable 3D organs for medical implantation from a patient’s own cells, eliminating the need for organ donation, immune suppression and the problem of transplant rejection.”

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